pentobarbital decreases amounts of elvitegravir/cobicistat/emtricitabine/tenofovir DF by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Could bring on loss of virologic response and attainable resistance.pentobarbital will lower the level or effect of verapamil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use C… Read More